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Bacterial fermentation creates AdoB 12 and MeB 12 , which are converted to cyanocobalamin by the addition of potassium cyanide in the presence of sodium nitrite and heat

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Graphical Abstract Similar content being viewed by others Introduction The tight junction-connected, non-fenestrated brain capillary endothelial cells in cross-talk with the neighboring pericytes and astroglial endfeet create the dynamic anatomical and functional unit called as bloodbrain barrier (BBB) [1]