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Re-evaluate long-term need often and work with knowledgeable clinicians to mitigate risks and adjust dosing according to response and goals

Moreover, there were consistently larger proportions of patients covered by treatment than there were patients who had not discontinued treatment (estimated as 1 minus the cumulative incidence of treatment discontinuation) for both study drugs, with these differences increasing over the follow-up period

The regulatory difference matters for formal weight-management indications and sometimes for insurance reimbursement

Remember, sustainable weight loss is a gradual process