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The Role of P450 Enzymes in Detoxification and Methylation Pathways In addition to the previously discussed detoxification pathways of methylation and glutathione, P450 enzymes also play a crucial role in detoxification

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Through these mechanisms, GPX4 establishes the redox threshold that separates cell survival from lipid peroxidation-induced death, functioning as the master regulator of ferroptosis

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