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Patients with personal/family history of medullary thyroid carcinoma or MEN2 syndrome are not candidates

This balancing act is critical because glucagon classically raises blood glucose (opposing insulin's effects), but when combined with GLP-1 agonism, the glucose-raising effects are counteracted while the metabolic benefits of increased energy expenditure and hepatic fat burning are preserved

Transmission cluster analysis Transmission clusters (TCs: include pairs and clusters 3) were identified in the ML tree using Cluster picker v1.2.3 100 with thresholds for bootstrap supports and genetic distances set at 90% and 4.5% respectively

Moreover, clinical trials have demonstrated its effectiveness, particularly when combined with lifestyle modifications such as a healthy dit and increased physical activity

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