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Combining a GLP-1 with insulin or certain other diabetes drugs can push blood sugar too low, which is exactly the kind of thing a doctor adjusts for before you take a first dose

These findingsoriginating from landmark trials such as EMPA-REG OUTCOME, LEADER, and SUSTAIN-6have led to substantial revisions in international guidelines from the European Society of Cardiology, American College of Cardiology, and American Heart Association, which now recommend the use of SGLT2i or GLP-1 RAs, often in conjunction with metformin

Alcohol is a known gastric irritant that can independently increase burping, bloating, and digestive discomfort

doi: 10.1002/mds.27466 21

Some people dont lose weight at all, and in fact, they gain weight