Participants who prematurely discontinued semaglutide were switched to another glucose-lowering drug at the investigators discretion
According to an estimate from the Centers for Disease Control, obesity is directly responsible for more than $140 billion in medical costs each year primarily for the treatment of weight-related diseases like heart disease, type-2 diabetes, and stroke
Across the market as of April 2026, monthly totals commonly range from roughly $200 to $700+ depending on product, tier, and dispensing pathway
Appetite response is dose-dependent, and many patients do not experience meaningful suppression until the mid-to-high range
503A patient-specific compounding by state-licensed pharmacies operates under a separate framework, though that framework also has restrictions when FDA-approved versions of a drug are available