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doi:10.1056/NEJMoa2502928 Bernardi M, et al

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Patients considering this combination should require close monitoring of liver and kidney function, blood glucose, and cortisol levelstesting most independent practitioners cannot reliably coordinate

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By Lana Pine | Published on September 16, 2025 4 min read Overall, GLP-1 receptor agonists (GLP-1 RAs) appear to be effective and relatively safe for kids and teens, at least in the short term, in helping with blood sugar control, weight and heart-related health risks, according to a new study published in JAMA Pediatrics