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Several trials are underway to evaluate anti-amyloid antibodies in combination with other agents such as anti-tau agents and antisenescence agents (Cummings et al., 2024), and a trial evaluating the combination of a multidomain lifestyle intervention and metformin (an antidiabetes drug) was recently initiated (Barbera et al., 2023)

As such, MCF7 cells were chosen for detailed studies of the effect of the synthetic catalyst since these cells were likely to contain the highest level of intracellular catalyst

Brown at Johns Hopkins University School of Medicine

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