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Participants began treatment with either cognitive behavioral therapy or fluoxetine, an antidepressant medication

Phentermine is an appetite suppressant that is typically used for the short term because of safety concerns in patients with heart conditions

These stressors affect more strongly: Deprived socio-economic groups Patients dealing with food insecurity Those experiencing recent stressful life events This combination creates a risk profile that helps identify patients who need additional monitoring or support while taking semaglutide