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Vehicle controls in matched PBS-BSA buffer, selective GLP-1R antagonist exendin(9-39) confirming GLP-1R-specific contributions, selective GIPR antagonist confirming GIPR-specific contributions, Semaglutide at equivalent molar concentration as the GLP-1R monoagonism reference, native GLP-1 with DPP-IV inhibitor as the endogenous GLP-1R reference, and native GIP as the endogenous GIPR reference

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Lowering dielectric strength of the medium from 80 (water) to 35 (PVP/glycerol/water formulations) led to about a sixfold decrease in peptide deamidation rates (54)

Medication modification will likely be accompanied by a conversation about lifestyle factors, such as eating and exercise

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