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Quercetin exerts neuroprotective effects through the upregulation of p-Akt expression, downregulation of p-ASK1, p-JNK3, and cleaved caspase-3 expression, and inhibition of neuronal apoptosis (Pei et al., 2016)

Handling technique is a stability question too: diluent is directed down the inside wall of the vial rather than onto the powder pellet, and the vial is swirled gently rather than shaken, because agitation can shear peptide bonds

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