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Western blot analysis revealed suppression of TNF-, COX-2, and nitric oxide synthase protein expression, indicating effective inhibition of inflammation-related signaling pathways

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Wilding J.P.H., Batterham R.L., Calanna S., et al

Read review Dihexa for Migraine & Chronic Migraine The May 2024 NICE TA973 atogepant (Aquipta, AbbVie) approval, the rimegepant / erenumab / galcanezumab / fremanezumab / eptinezumab CGRP pathway, 2025 chronic-migraine hippocampal atrophy & accelerated brain ageing research, the Tanure BDNF-elevated-in-attack paradox, NICE NG150, and the ~10 million UK migraine population