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Abstract PG-102 is a potency-optimized bispecific Fc fusion protein targeting GLP-1 and GLP-2 receptors

High-fat processed foods (particularly trans fats and refined vegetable oils), ultra-processed carbohydrates, and excess fructose from sugary drinks and packaged juices have been associated with impaired GLP-1 response and faster GLP-1 breakdown

La titolazione prevede un incremento di dose dopo almeno 30 giorni a ciascun livello, sulla base della tollerabilit e della risposta clinica

GLP-1 agonists are a class of medications that mimic the action of the hormone GLP-1 (glucagon-like peptide-1), which is involved in insulin production and appetite regulation

95% CI, 0.87-0.94), as were the risks for chronic kidney disease (HR = 0.97