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Chris Masterjohn wrote an excellent review of this study and proposes other interesting possibilities, including gender differences and vitamin deficiency issues

3B, C and Supplementary Fig

After adjustments, the anastrozole group weighed 0.1 kg less on average and had 0.1 kg more body fat and 0.3 kg less FFM than the placebo group at this timepoint, but none were statistically significantly different (body weight 95 % CI 1.29 to 1.08, body fat 0.75 to 0.96, FFM 0.79 to 0.19)

Tirzepatide may be the most effective as it also enhances the activity of the GIP receptor, glucagon receptor, and/or amylin receptor

Forst T, Nguyen M, Forst S, Disselhoff B, Pohlmann T, Pfutzner A