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Losartan is an angiotensin II receptor blocker (ARB) widely prescribed in the UK for conditions including hypertension, diabetic nephropathy, and where ACE inhibitors are not tolerated heart failure, in line with the British National Formulary (BNF) and UK Summary of Product Characteristics (SmPC)

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The GLP-1R is expressed in many tissues, including pancreatic islets, the central nervous system, lung, kidney, heart, intestine, and also on immune cells (49, 50), underlining the numerous roles for GLP-1-signaling beyond blood glucose control

This makes it more than just symptom control, it could potentially slow disease progression