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Does hypothyroidism slow down weight loss with semaglutide

Wegovy is a GLP-1 receptor agonist, a type of medication that mimics a natural hormone called GLP-1 (glucagon-like peptide-1)

In the SURMOUNT-1 study, in fact, over 95% of participants with prediabetes were able to achieve normalization of blood glucose after 72 weeks of treatment with tirzepatide, the first GIP/GLP-1 receptor co-agonist representing this new class of drugs, compared to 62% of the control group [57]

They are not associated with cardiovascular protection beyond glucose lowering, so they are typically chosen when GLP-1 agonists or SGLT2 inhibitors are unsuitable

Previous studies have shown isolated mitochondria are able to import glutathione 11 , but the transporter machinery responsible for this activity has remained elusive