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In this rather important subgroup analysis based on high-quality RCT data from STRIDE, we showed that the benefit on objective walking capacity from treatment with semaglutide in persons with earlier stage PAD and concurrent T2DM was consistent across age groups and across a range of clinical markers of PAD severity, including in persons that had previously undergone a lower limb revascularisation procedure
Clinical trials involving the active ingredients in these medications have shown remarkable results
A clinical trial showed that people taking GLP-1 medications experienced increased metabolic activity alongside weight loss [4]
Anal Chem 87(5):28782883
Combining them would negate the primary advantage of the peptide approach
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