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Compounded medications are prepared by FDA-registered, inspected compounding pharmacies

Microbiota imbalances activate the inflammatory responses in the pancreas, leading to the accumulation of inflammatory cells and pro-inflammatory factors

Semaglutide and liraglutide activate GLP-1 receptors to suppress appetite

Acknowledgements The authors would like to thank Xiaotong Zhangs lab at Zhejiang University for the technical support in data acquisition

Drugs that mimic the bodys natural GLP-1 hormone have been around since 2005, but tirzepatide was the first to target both GLP-1 and the GIP receptors, which act in synergy with GLP-1 and help stimulate insulin release