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Physical examination revealed dry skin, areas of atrophic skin with a cigarette-paper-like appearance, sun-tan-like hyperpigmentation, and telangiectasias predominantly in photo-exposed areas, as well as pseudosyndactyly of the hands and punctate keratotic papules on the soles of the feet (Figs
Kirtane, A
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NNK was also shown to inflict cellular damage in the pancreas (vacuolization, pyknotic nuclei, and edema) after a two week treatment period in rats
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