how long before surgery should i stop taking glp 1 If you’re a GLP-1 medication and planning plastic surgery, timing matters more than most patients realize. ⁠, ⁠, Denver plastic surgeon Dr. Philippe Capraro of @grossmancapraroplasticsurgery Stopping GLP-1 Prior to Surgery:

A study reported that there was no difference in post-prandial plasma incretin concentrations between diffuse and focal cases, and no difference in baseline plasma incretin concentration between focal, diffuse, and transient hyperinsulinism ( Studies in a mouse model of K ATP hyperinsulinism, the most common and severe genetic subtype of hyperinsulinism, have shown that the GLP-1 receptor antagonist exendin-(9-39) significantly increases fasting plasma glucose and decreases the insulin to glucose ratio on the fasting state, effectively reversing the hyperinsulinemic hypoglycemia phenotype

This is especially important if you notice multiple symptoms togethersuch as significant abdominal weight gain, muscle weakness, easy bruising, or missed periodsor if you suspect a more serious condition like Cushings syndrome

Finally, keep fats modest

Cardiorenal outcomes with dapagliflozin by baseline glucose-lowering agents: Post hoc analyses from DECLARE-TIMI 58

Effects of one year treatment of vildagliptin added to pioglitazone or glimepiride in poorly controlled type 2 diabetic patients