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Its relevance to neuropathy is most direct in the metabolic neuropathies, particularly diabetic peripheral neuropathy, where impaired glucose metabolism, insulin resistance, and mitochondrial dysfunction all contribute to nerve damage

[Google Scholar] 3.Khavinson V.K., Morozov V.G

Morning administration in a fasted state is the most commonly cited timing because endogenous fat mobilisation is naturally elevated after an overnight fast, theoretically amplifying the lipolytic signal from the peptide