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Unlike earlier generation secretagogues, Ipamorelin is highly selective and does not cause significant spikes in cortisol or prolactin, making it a preferred subject for metabolic research

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Arshad MT et al

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The BPROAD study [28] included 12,821 patients with type 2 diabetes and hypertension aged 50 years or older, and 48% were aged above 65 years

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Weaker candidates People with significant GI sensitivity to tirzepatide who are already struggling with nausea, diarrhea, or abdominal pain should probably avoid adding another compound that can worsen those symptoms

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