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The up-regulation of a GST gene was observed also in A

Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]

Furthermore, because fasting values affect the increase in postmethionine-load homocysteine, the percent rise of homocysteine above fasting should be taken into account when assessing the cardiovascular risk