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5.2.1.2 Antioxidant synergy Optimizing antioxidant combinations, such as chlorogenic acid, curcumin, and -mercaptoethanol, may amplify protection against oxidative damage during embryo development

Then what we do in humans is we kind of rely on our best proxy biomarkers that we think reflect the systems that drive aging and we can measure those things over time and sort of estimate what we think is the effective this dietary change or that dietary change or this lifestyle change or that drug change on those things

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My TSH and T4 have never been that far out of range but with the proper testing I found Hashimotos, which explained my constant fatigue and irregular periods (they can be anywhere from 14 days to 50+ and last 2-3 days or up to 10, and be very heavy or very light, truly irregular in all manner of ways!) Oh and folate needs testing too

Department of Veterans