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The researchers excluded individuals who previously used GLP-1 RAs, and those with drug contraindications, such as gastroparesis, diabetic ketoacidosis, thyroid cancer, pancreatitis, severe hypoglycemia, or severe renal impairment

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2.2 Experimental design Forty male Sprague Dawley rats (150 10 g) were acclimatized for 1 week with free access to standard feed and water under sanitary conditions ( After this week, the rats were arbitrarily allocated into four groups, each including 10 rats

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When prescribed and monitored by a medical provider, tirzepatide can help patients achieve meaningful, long-term results safely and effectively

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