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The second effect is that our waste products move more slowly through the gastrointestinal tract

Possible neuroendocrine regulation of GLP-1 secretion is supported by studies in rodents in which nutrient flow to the distal intestine is prevented, precluding direct L-cell contact in this part of the intestine to luminal nutrients, [289,320]

The length of treatment varies by individual, but many patients see significant results within a few months

It is sometimes used off-label in adults to support body composition and anti-aging goals

Patients may feel the medication works less dramatically over time because they have adapted to its effects