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Pathogenetic and therapeutical uncertainties

HA is an essential component of the joints synovial fluid that reduces cartilage friction

This range extrapolates from effective animal doses using standard interspecies scaling calculations

This is not surprising, given that most of the attempted reproductions were performed long before the development of many physical, chemical, and cytological concepts necessary to interpret the underlying processes

Memory, attention, and information processing all improve alongside anxiety reduction, suggesting the effects are not simply removing anxiety-induced impairment but actively enhancing underlying cognitive capacity