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Individuals with hypothyroidism should have thyroid function optimized before starting Sermorelin as GH can affect thyroid hormone metabolism and requirements

Likewise, to avoid unpleasant side effects of systemic carbonic anhydrase inhibition, carbonic anhydrase inhibitors, since acetazolamide (topical administration with little or no effect on intraocular pressure) [68,69], were used for a long period before a topical carbonic anhydrase inhibitor was realized (dorzolamide) [70,71]

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Drink plenty of fluids to avoid dehydration