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[112] describe how lithium may be related to aging processes that involve protein secretion, ultimately resulting in neurodegenerative diseases such as Parkinsons Disease (PD)

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In a later study, similar sensors were made to image Rac1 activity during sLTP in hippocampal neurons, and it was found that Rac1 was also required for the transient and sustained spine enlargement (Hedrick et al., 2016)

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