Recently, in addition to the central maintenance of food intake, GLP-1R signaling has begun to be considered in the context of the regulation of the stress response, as it is indicated that it can activate both the hypothalamicpituitaryadrenal (HPA) axis as well as the sympathetic nervous system [15, 16]
Methods: A comprehensive literature search was performed across multiple medical databases, including Embase, Medline, and Cochrane to look for English articles on interventions with SGLT2 inhibitors, GLP-1, and dual gastric inhibitory polypeptide/GLP-1 receptor agonists in people living with sleep apnea and overweight or obesity
Kidney problems Usually related to dehydration from vomiting or diarrhea
It works by replicating the bodys natural hormone GLP-1, which is responsible for regulating appetite, digestion, and blood sugar balance
This means more frequent vomiting episodes and greater nutrient loss through the GI tract during dose titration