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L81 encompasses Other disorders of pigmentation, while L81.4 specifically captures melanin hyperpigmentation not elsewhere classified

The mechanism of action is more likely related to altered hypoxic and hypercapnic ventilatory response with testosterone administration, though work is still needed to resolve inconsistencies in currently available studies

doi: 10.14202/vetworld.2016.1287-1293 25 QureshiMAGarlichJDKiddMT

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