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Accordingly, acute administration of liraglutide may attenuate intestinal tight junction gene levels via an LPS- and TLR4-dependent mechanism and promote BT under stress conditions, such as those found in the colitis model

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Titration, the process of slowly increasing dosage over time and only when the medication is well-tolerated, helps manage GLP-1 side effects

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More data are needed to clarify the effects of GLP-1RAs on the incidence of OA, RA, PsA and axSpA, as well as on disease activity and progression in these conditions