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Ongoing pressure keeps stress hormones elevated, which over time can affect sleep, digestion, blood pressure, and the immune system, so calming the mind alone is rarely enough

For example, patients with systemic primary carnitine deficiency (SPCD) have a deficiency in carnitine due to a mutation in the plasma membrane sodium-dependent high affinity carnitine transporter (OCTN2) that enables cellular carnitine uptake in the heart, muscle, and kidney

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