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4a, upper chromatogram), but after 1 h of incubation with glucosidase, the first peak, eluting after 1.7 min and representing the paracetamolglucose, completely disappears as a result of hydrolyzing the ester bond between glucose and acetaminophen (see Fig

in room air prior to ten days of IH exposure and were sacrificed immediately following the conclusion of IH (Fig

The 2HG content of experimental samples was determined by interpolation using 2HG peak areas measured in the standards

Melatonin also prevents the opening of the mitochondrial permeability transition pore (mPTP) and activates AMPK, promoting cellular energy balance and mitochondrial biogenesis (Ozkok et al., 2016)

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