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The final pellets composed by liver mitochondria were suspended in medium devoid of EGTA and BSA in a final protein concentration of 50 mg/mL

M., & Zhang, C

And so, it's a tough fight, but you're paving the way here

Any fraction that is not conjugated, then undergoes CYP 450 metabolic pathway being converted to cytotoxic metabolite, N-acetyl-p-benzoquinone-imine (NAPQI)