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[1] This mechanism reduces the risk of hypoglycemia when used alone, though this risk increases when combined with insulin or sulfonylureas

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However, the evidence is still evolving related to how these medications may impact complications related to obesity such as heart disease and diabetes. The Pharmaceutical Strategies Group (PSG), a pharmaceutical management consulting company, surveyed 180 benefits executives representing health plans, employers and unions and found that these drugs are a major concern

If they are not improving, or they are getting worse, that is worth raising with your prescriber or pharmacist (see when to check with a clinician, above)