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Tirzepatide, on the other hand, works by binding to the melanocortin-3 and melanocortin-4 receptors in the brain, which helps reduce food intake and increase energy expenditure

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R The glutathione conjugate is then processed through the mercapturic acid pathway: gamma-glutamyl transpeptidase (GGT) on the external surface of renal and biliary epithelia cleaves the gamma-glutamyl bond, aminopeptidase M removes glycine, and cytosolic N-acetyltransferase acetylates the remaining cysteine to form the mercapturic acid

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