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The loss of ALOX12 inhibits p53-mediated ferroptosis and accelerates tumor progression
This fermentation produces SCFAs such as acetate, propionate, and butyrate
In a German multicenter phase IIa clinical trial, vilobelimab demonstrated both a satisfactory safety profile and a dosedependent improvement in organ dysfunction among patients with severe sepsis, while maintaining normal membrane attack complex (MAC) formation [358]
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