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Description

Complete 16 consecutive weekly doses as directed

A summary of these cutaneous reactions is presented in Table 1

Beyond genetics, lifestyle factors play a role: patients who are sedentary, have higher baseline anxiety, or are rapidly escalating their dose often report more noticeable heart rate increases

Nicotera et al., 2003

This initial dose serves primarily as a tolerability step, allowing the gastrointestinal system to adapt to the medication and minimising adverse effects such as nausea and vomiting