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Description

Clinical, Cosmetic and Investigational Dermatology, 10, 147153

Route of Elimination Following a single intravenous dose, 73.1 +/- 16% of the dose was excreted in the urine during the 0-24 hour interval

Heart rate increases were dose-dependent and followed a consistent pattern across all treatment groups

Other substances (nicotine, etc.): Preclinical studies indicate GLP-1 activation reduces nicotine intake in animals, and early human signals suggest broader reductions in reward-driven behaviors (MDPI 2025)