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The European Food Safety Authority (EFSA) issued a 2018 scientific opinion concluding that GTE doses at or above 800 mg EGCG/day were associated with "liver safety concerns" and that doses above 400 mg EGCG/day in supplements "could not be considered safe" for regular use [6]

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For liposomal Glutathione for autoimmune flare control, its a flare-tamer, with glutathione supplement for inflammation proving safe alongside methotrexateGlutathione with methotrexate safety confirmed in adjunct studies, sans interactions [7]