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NAC may cause nausea, particularly at higher doses, and has a characteristic sulphur odour that some individuals find unpleasant
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The importance of adhering to regular daily treatment, the need to titrate the dose over time depending on serum urate levels and a commitment to lifelong use That urate-lowering treatment should be continued during future flares (assuming they have been adherent in the weeks and months leading up to the event)
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