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Treatment of Drosophila flies with kynurenine pathway inhibitors and the NAD + precursors NR or NAM increased the lifespan of these animals, suggesting an advantage in combining different therapeutic strategies

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These include the competing effects of the formation of cobalamin-like molecules in our body (the so-called cobalamin analogues or pseudo-cobalamins), which may impair the proper action of the good cobalamin