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Here, they are rapidly oxidized, recognized by scavenger receptors, and then phagocytosed by macrophages and macrophage-like VSMCs, which induces foam cell formation and plaque progression 65

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Arterioscler Thromb Vasc Biol 20:21752183

Angiotensin IV (Val 1 -Tyr 2 -Ile 3 -His 4 -Pro 5 -Phe 6 ) is an endogenous hexapeptide fragment of the renin-angiotensin system, historically considered a metabolite of angiotensin II but subsequently shown to have independent procognitive activity in rodent models