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4.3 Diabetic cardiomyopathy Extensive evidence supports the broad-spectrum cardioprotective properties of GLPs, which effectively counteract diverse cardiac pathologiessuch as pathological myocardial hypertrophy, viral or autoimmune myocarditis, atherosclerotic plaque development, sepsis-associated myocardial depression, ischemia-reperfusion injury, and cardiotoxicity triggered by chemotherapeutic agents (Ubaidillah et al., 2016

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The antioxidant capacity of silymarin can lower oxidative stress (in the liver) associated with acetaminophen metabolism in rats, which has the effect of conserving cellular glutathione levels (Campos 1989)