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First, the single-center design and retrospective nature pose the risk of introducing biases, thus further prospective and multi-center studies with larger and adjusted cohorts are needed to validate our findings

LAR: Leucoanthocyanidin reductase

# indicate significant difference (P0.05) from 5 mol/ml ASA treated group and indicate significant difference (P0.05) as compared to 10 mol/ml ASA treated group