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Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

This process plays a crucial role in maintaining the balance between erythropoiesis and RBC destruction

26, 27 Furthermore, it is known that GPxs are involved in the regulation of platelet activity, endothelial function, platelet-dependent thrombosis and propensity for vascular thrombosis, and a deficiency of this enzyme has been associated with platelet-dependent thrombosis and arterial ischemic stroke

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Melatonin enhances salt stress tolerance in rubber tree ( Hevea brasiliensis ) seedlings