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Finally, countries experiencing a new rise of SARS-CoV-2 positive cases such as the four major EU nations and UK, should promote the development of more rational treatment guidelines for COVID-19, taking due account of the above facts and considerations to avoid that the same mistakeif concerns on PAC are ascertainedmay be repeated in the next few months

This may limit the capacity to neutralize ROS and RNS, thereby facilitating further formation of dsNNTTR

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