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Data Animal Data: In a combined fertility and embryofetal development study in rats, subcutaneous doses of 0.01, 0.03 and 0.09 mg/kg/day (0.2-, 0.7- and 2.1-fold the MRHD) were administered to males for 4 weeks prior to and throughout mating and to females for 2 weeks prior to mating, and throughout organogenesis to Gestation Day 17
Ow/Ob 98.3 11.4 mg/dL
And this is the point of this, this is educational, right
Qsymia carries pregnancy risks (topiramate causes birth defects), a more complex side effect profile including cognitive effects from topiramate, and it requires participation in a REMS risk management program
Readers can compare these community views with their own expectations for Pfizer's ability to refresh its portfolio and protect margins
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