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TMAO causes oxidative stress and inflammation, which may offset the benefits of LC

10.1016/j.ctrv.2017.01.005 102 PozzoJ

In terms of chemical nature, ROS are a diverse set of oxidants that serve various physiological and biological roles, including signalling that causes cell damage [3]

This was followed by centrifugation and the supernatant was collected

However, certain disease states and drug therapies can influence intra-portal insulin levels and invariably alter the relationship between GH and IGF-I